Ectopic ACTH Syndrome

Also known as EAS

Sources of Ectopic ACTH production.

• Lung = most common cause.
• Thymus
• Thyroid – Medullary carcinoma
• Ovary
• Adrenal Gland – pheochromocytoma
• Liver
• Pancreas
• Other neuroendocrine cancers

Difference between Cushings syndrome and Cushings disease

• Cushings syndrome is cortisol excess from any cause.
• Cushings disease is cortisol excess by pituitary ACTH over-secretion

Presentation found on the internet regarding Ectopic ACTH production:

http://www.med.unc.edu/medicine/web/ectopicacth.pdf