GIST – Gastrointestinal Stromal Tumor
- GISTs may be malignant or benign
- More common in the stomach and small intestine but can be found anywhere along the GI tract.
- Begins in cells called th interstitial cells of Cajal (ICC) – considered the pacemakers of the GI tract
- GIST may have a genetic component. Neurofibromatosis type 1 is linked to GIST.
- Partial resections are usually adequate with GIST treatment with negative margins. Formal gastrectomy is not usually necessary, nor is partial gastrectomy with nodal dissection. Organ sparing approaches are usually appropriate.