Tumor of the beta cells of the pancreas

  • secretes insulin
  • Normally beta cells secrete insulin in response to high glucose in the blood stream.
  • Diagnosis is made with blood tests of low blood glucose, elevated insulin, and elevated proinsulin and C-peptide levels.
  • Steve Jobs of Apple died of Metastatic Insulinoma.
  • rarely malignant, metastasis and primary usually present concomitantly.
  • finding insulinoma near the pancreatic duct – this insulinoma might be malignant

Whipples Triad suggests insulinoma

  1. Symptoms of Hypoglycemia
  2. Low plasma glucose
  3. Relief of symptoms when glucose is raised to normal

Leave a Reply

Your email address will not be published. Required fields are marked *