{"id":155,"date":"2013-11-15T20:02:33","date_gmt":"2013-11-15T20:02:33","guid":{"rendered":"http:\/\/www.modestosurgery.com\/surgeryblog\/?p=155"},"modified":"2013-11-15T23:47:43","modified_gmt":"2013-11-15T23:47:43","slug":"hyperparathyroidism-primary-secondary-tertiary-simplified","status":"publish","type":"post","link":"http:\/\/www.modestosurgery.com\/surgeryblog\/hyperparathyroidism-primary-secondary-tertiary-simplified\/","title":{"rendered":"Hyperparathyroidism – primary, secondary, tertiary – simplified"},"content":{"rendered":"

The disease of hyperparathyroidism<\/strong> is diverse. \u00a0The causes of it are very different. \u00a0As a simplification there’s primary, secondary and tertiary hyperparathyroidism:<\/p>\n

All three of these involves increased PTH (parathyroid hormone)<\/p>\n

Primary<\/strong>: elevated calcium, low phosphorus in blood stream. \u00a0Usually caused by a parathyroid adenoma.<\/p>\n

Secondary<\/strong>: normal or low calcium, usually caused by renal failure.<\/p>\n

Tertiary<\/strong>: failure of treatment of secondary hyperparathyroidism to correct increased PTH.<\/p>\n

More details on hyperparathyroidism<\/h3>\n

Primary hyperparathyroidism is most commonly caused by adenomas, greater than 85%. \u00a0Next most common cause would be hyperplasia which is 10% of the causes, and there is a 1% possibility that primary hyperparathyroidism is caused by a carcinoma.<\/p>\n

Risk factor for primary hyperparathyroidism includes family history, MEN I and MEN IIa, and also radiation. \u00a0Major difference between MEN IIA and IIB: \u00a0MEN IIA has Hyperparathyroidism \u2013 hyperplasia, MEN IIB does not. \u00a0More on MEN syndromes<\/a>.<\/p>\n

Sestamibi scan<\/a> is a method of detecting hyperparathyroidism.<\/p>\n

Carcinomas which are commonly associated with hypercalcemia:<\/h3>\n