{"id":148,"date":"2013-10-27T01:30:00","date_gmt":"2013-10-27T01:30:00","guid":{"rendered":"http:\/\/www.modestosurgery.com\/surgeryblog\/?p=148"},"modified":"2013-10-27T01:30:00","modified_gmt":"2013-10-27T01:30:00","slug":"somatostatinoma-glucagonoma-insulinoma-vipoma-gastrinoma","status":"publish","type":"post","link":"http:\/\/www.modestosurgery.com\/surgeryblog\/somatostatinoma-glucagonoma-insulinoma-vipoma-gastrinoma\/","title":{"rendered":"Somatostatinoma, Glucagonoma, insulinoma, vipoma, gastrinoma"},"content":{"rendered":"<h1>Pancreas NeoEndocrine\/Islet cell Tumors<\/h1>\n<p>Sometimes associated with <a href=\"http:\/\/www.modestosurgery.com\/surgeryblog\/multiple-endocrine-neoplasias\/\">MEN I (multiple endocrine neoplasia)<\/a><\/p>\n<h3>Somatostatinoma<\/h3>\n<ul>\n<li>tumor of the delta cells of the endocrine pancreas<\/li>\n<li><strong>triad of: Diabetes Mellitus, Steatorrhea, and Gallstones<\/strong><\/li>\n<li>Most are malignant and have metastasized<\/li>\n<\/ul>\n<h3>Glucagonoma<\/h3>\n<ul>\n<li><strong>Necrolytic Migratory Erythema (NME)<\/strong>. \u00a0found in 70%<\/li>\n<li>Diabetes Mellitus<\/li>\n<li>Most are malignant and have metastasized<\/li>\n<\/ul>\n<h3>VIPOMA<\/h3>\n<ul>\n<li>Vasoactive Intestinal Polypeptide tumor<\/li>\n<li>Verner Morrison syndrome<\/li>\n<li>Causes WDHHA: \u00a0<strong>Watery Diarrhea<\/strong>, Hypokalemia, Hypochlorhydria, Achlorhydria<\/li>\n<li>Activation of cellular adenylate cyclase and cAMP production<\/li>\n<li>50% malignant<\/li>\n<\/ul>\n<h3><a title=\"insulinoma\" href=\"http:\/\/www.modestosurgery.com\/surgeryblog\/insulinoma\/\">Insulinoma<\/a><\/h3>\n<ul>\n<li>10% malignant<\/li>\n<li>Whipple&#8217;s triad of pancreatic insulinoma &#8211; Hypoglycemia, symptoms of hypoglycemia, relief of symptoms when glucose is given.<\/li>\n<\/ul>\n<h3>Gastrinoma<\/h3>\n<ul>\n<li>Zollinger-Ellison Syndrome<\/li>\n<li>Excess gastric acid production<\/li>\n<li>Can arise in the duodenum or pancreas<\/li>\n<li>60% malignant<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pancreas NeoEndocrine\/Islet cell Tumors Sometimes associated with MEN I (multiple endocrine neoplasia) Somatostatinoma tumor of the delta cells of the endocrine pancreas triad of: Diabetes Mellitus, Steatorrhea, and Gallstones Most are malignant and have metastasized Glucagonoma Necrolytic Migratory Erythema (NME). \u00a0found in 70% Diabetes Mellitus Most are malignant and have metastasized VIPOMA Vasoactive Intestinal Polypeptide &hellip; <a href=\"http:\/\/www.modestosurgery.com\/surgeryblog\/somatostatinoma-glucagonoma-insulinoma-vipoma-gastrinoma\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Somatostatinoma, Glucagonoma, insulinoma, vipoma, gastrinoma<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-148","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/posts\/148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/comments?post=148"}],"version-history":[{"count":1,"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/posts\/148\/revisions"}],"predecessor-version":[{"id":149,"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/posts\/148\/revisions\/149"}],"wp:attachment":[{"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/media?parent=148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/categories?post=148"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.modestosurgery.com\/surgeryblog\/wp-json\/wp\/v2\/tags?post=148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}